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Observe Carefully (1)pentobarbital will decrease the extent or influence of levamlodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital decreases effects of sufentanil SL by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Coadministration of CYP3A4 inducers may possibly lessen sufen